Essentielle fedtsyrer, forskningsreferencer
Januar 1999
1. Adler AJ, Holub BJ: Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men. Am J Clin Nutr 65:445-450, 1997.
2. Albert CM, Hennekens CH, Willett WC, Manson JE, et al.: Fish consumption and risk of sudden cardiac death. JAMA 279:23-28, 1998.
3. Amusquivar E, Ruperez FJ, Barbas C, Herrera E: Low arachidonic acid rather than alpha-tocopherol is responsible for the delayed postnatal development in off… J Nutr 130:11:2855-65, 2000.
4. Annuzzi G, Rivellese A, Capaldo B, Di Marino L, et al.: A controlled study on the effects of n-3 fatty acids on lipid and glucose metabolism in non-insulin-dependent diabet. Atherosclerosis 87:1:65-73, 1991.
5. Appel LJ: The effect of omega-3 polyunsaturated fatty acids on blood pressure. Omega-3 News:1:1-4 , 1994.
6. Ariza-Ariza R, Mestanza-Peralta M, Cardiel MH: Omega-3 fatty acids in rheumatoid arthritis: an overview. Semin Arthritis Rheum 27:6:366-370, 1998.
7. Ascherio A, Rimm EB, Stampfer MJ, Giovannucci EL, et al.: Dietary intake of marine n-3 fatty acids, fish intake, and the risk of coronary disease among men. N Engl J Med 332:15:977-982, 1995.
8. Bagga D, Capone S, Wang HJ, Glaspy JA, et al.: Dietary modulation of omega-3/omega-6 polyunsaturated fatty acid ratios in patients with breast cancer. J Natl Cancer Inst 89:15:1123-31, 1997.
9. Barham JB, Edens MB, Fonteh AN, Johnson MM, et al.: Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid… J Nutr 130:8:1925-1931, 2000.
10. Bartels M, Nagel E, Pichlmayr R What is the role of nutrition in ulcerative colitis? A contribution to the current status of diet therapy in treatm. Langenbecks Archiv fur Chirurgie 380:1:4-11, 1995.
11. Begin ME, Das UN, Ells G, Horrobin DF: Selective killing of human cancer cells by polyunsaturated fatty acids. Prostaglandins Leukotrienes and Medicine 19:177-186, 1985.
12. Begin ME, Das UN: A deficiency in dietary gamma-linolenic and/or eicosapenta- enoic acids may determine individual susceptibility to AIDS. Medical Hypotheses 20 20:1-8, 1986.
13. Belluzzi A, Brignola C, Campieri M, Pera A, et al.: Effect of an enteric-coated fish-oil preparation on relapses in Crohn’s disease. New England Journal of Medicine 334:24:1557-60, 1996.
14. Berth-Jones J, Graham-Brown RA: Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis published erratum appea. Lancet 341:8860:1557-1560, 1993.
15. Bittiner SB, Tucker WF, Cartwright I, Bleehen SS: A double-blind, randomised, placebo-controlled trial of fish oil in psoriasis. Lancet 1:8582:378-380, 1988.
16. Bjørneboe A, Søyland E, Bjørneboe GE, Rajka G, et al.: Effect of dietary supplementation with eicosapentaenoic acid in the treatment of atopic dermatitis. Br J Dermatol 117:4:463-469, 1987.
17. Bonefeld-Jørgensen EC, Møller SM, Hansen JC: Modulation of atherosclerotic risk factors by seal oil: a preliminary assessment. International. J. of Circumpolar Health 60:25-33, 2001.
18. Brown JE, Wahle KW: Effect of fish-oil and vitamin E supplementation on lipid peroxidation and whole-blood aggregation in man. Clin Chim Acta 193:3:147-56, 1990.
19. Brown M: Do vitamin E and fish oil protect against ischaemic heart disease? Lancet 354:441-442, 1999.
20. Burkow IC, Henderson RJ: Analysis of polymers from autoxidized marine oils by gel permeation HPLC using a light-scattering detector. Lipids 26:3:227-231, 1991.
21. Cathcart ES, Mortensen RF, Leslie CA, Conte JM, et al.: A fish oil diet inhibits amyloid P component (AP) acute phase responses in arthritis susceptible mice. J Immunol 139:1:89-91, 1987.
22. Cathcart ES, Gonnerman WA, Leslie CA, Hayes KC: Dietary n-3 fatty acids and arthritis. J Intern Med Suppl 225:731:217-23, 1989.
23. Cathcart ES, Gonnerman WA: Fish oil fatty acids and experimental arthritis. Rheum Dis Clin North Am 17:2:235-242, 1991.
24. Christensen M S, Mortimer B, Høy C, Redgrave T G: Clearance of Chylomicrons following Fish Oil and seal Oil Feeding Nutr. Res. 15:3:359-368, 1995.
25. Cleland LG, Hill CL, James MJ: Diet and arthritis. Baillieres Clin Rheumatol 9:4:771-85, 1995.
26. Cleland LG, French JK, Betts WH, Murphy GA, et al.: Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. J Rheumatol 15:10:1471-5, 1988.
27. Cleland LG, Gibson RA, Neumann M, French JK: The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids. Prostaglandins Leukot Essent Fatty Acids 40:1:9-12, 1990.
28. Cleland LG, James MJ: Rheumatoid arthritis and the balance of dietary N-6 and N-3 essential fatty acids :editorial. Br J Rheumatol 36:5:513-4, 1997.
29. Christensen JH, Aaroe J, Knudsen N, Dideriksen K, et al.: Heart rate variability and n-3 fatty acids in patients with chronic renal failure–a pilot study. Clinical Nephrology 49:2:102-106, 1998.
30. Christensen JH, Christensen MS, Dyerberg J, Schmidt EB: Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n-3 fatty acids. Am J Clin Nutr 70:3:331-7, 1999.
31. Christensen JH, Gustenhoff P, Korup E, Aarøe J, et al.: Effect of fish oil on heart rate variability in survivors of myocardial infarction. BMJ 312:677-78, 1996.
32. Christophe A: Effects of feeding a supplement of gamma-linolenic acid containing oils with fish oil on the fatty acid composition. In: Gamma-Linolenic Acid, ed. Yung-Sheng Huang, D.:168-174, 1996.
33. Connor SL, Connor WE: Are fish oils beneficial in the prevention and treatment of coronary artery disease?. Review[53 refs] American Journal of Clinical Nutrition 66:4 Suppl:1020S-1031, 1997.
34. Connor W: Fish oil prevents death from heart disease. PUFA Newsletter 3:3:1 (1999)
35. Connor WE: Importance of n-3 fatty acids in health and disease. Am J Clin Nutr 71:1 Suppl:171S-5S, 2000.
36. Darlington G, Jump A, Ramsey N: Dietary treatment of rheumatoid arthritis. Practitioner 234:1488:456-460, 1990.
37. Das G: Fish oil in heart disease. Int J Clin Pharmacol Ther Toxicol 27:12:569-77, 1989.
38. D’Aquino M, Benedetti PC, Di Felice M, Gentili V, et al.: Effect of fish oil and coconut oil on antioxidant defence system and lipid peroxidation in rat liver. Free Radic Res Commun 12-13 Pt 1:147-152, 1991.
39. de Deckere EA: Possible beneficial effect of fish and fish n-3 polyunsaturated fatty acids in breast and colorectal cancer. Eur J Cancer Prev 8:3:213-21, 1999.
40. de Deckere EA, Korver O, Verschuren PM, Katan MB: Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. Eur J Clin Nutr 52:10:749-753 , 1998.
41. Dehmer GJ, Popma JJ, van den Berg EK, Eichhorn EJ, et al.: Reduction in the rate of early restenosis after coronary angioplasty by a diet supplemented with n-3 fatty acids. N Engl J Med 319:12:733-40 (1988)
42. Deutch B, Bonefeld Jørgensen E, Hansen JC: Menstrual discomfort in Danish women reduced by dietary supplements of omega-3 PUFA and B12 (Fishoil or Sealoil)
43. Rome: Women’s Health in the Year 2000 (conf. paper:1 (1998)
44. Deutch B, Jørgensen EB, Hansen JC: N-3 PUFA from fish-oil or seal-oil reduce atherogenic risk indicators in Danish women. Nutrition Research 20:8:1065-1077 (2000)
45. Deutch B, Jørgensen EB, Hansen JC: Menstrual discomfort in Danish women reduced by dietary supplements of omega-3 PUFA (fish-oil or seal-oil) and B12. Nutrition Research 20:5:621-631 (2000)
46. Deutch B: Menstrual pain in Danish women correlated with low n-3 polyunsaturated fatty acid intake. European Journal of Clinical Nutrition 49:7:508-16 (1995)
47. DeLuca P, Rothman D, Zurier RB: Marine and botanical lipids as immunomodulatory and therapeutic agents in the treatment of rheumatoid arthritis. Rheum Dis Clin North Am 21:3:759-77 (1995)
48. Dolecek TA: An ongoing evaluation of dietary polyunsaturated fatty acids and mortality in the multiple risk factor intervention trial. Omega 3 News 7:4:1-3 (1992)
49. Dyerberg J: Bioavailability of n-3 fatty acid formulations. Annual Meeting, Eur Soc for Clin Invest:1-2 (1995)
50. El Boustani S, Colette C, Monnier L, Descomps B, et al.: Enteral absorption in man of eicosapentaenoic acid in different chemical forms. Lipids 22:10:711-4 (1987)
51. Endres S, Ghorbani R, Kelley VE, Georgilis K, et al.: The effect of dietary supplementation with n-3 PUFA’s on the synthesis of interleukin-1 and TNF… N Engl J Med 320:5:265-71 (1989)
52. Espersen GT, Grunnet N, Lervang HH, Nielsen GL, et al.: Decreased interleukin-1 beta levels in plasma from rheumatoid arthritis patients after dietary supplementation. Clin Rheumatol 11:3:393-5 (1992)
53. Fahrer H, Hoeflin F, Lauterburg BH, Peheim E, et al.: Diet and fatty acids: can fish substitute for fish oil? Clin Exp Rheumatol 9:4:403-6 (1991)
54. Fernandez E, Chatenoud L, La Vecchia C, Negri E, et al.: Fish consumption and cancer risk. Am J Clin Nutr 70:1:85-90 (1999)
55. Fish oil: Lancet 1:8594:1081-3 (1988)
56. Gadek JE, DeMichele SJ, Karlstad MD, Pacht ER, et al.: Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acut … Crit Care Med 27:8:1409-20 (1999)
57. Geusens P, Wouters C, Nijs J, Jiang Y, et al.: Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, contr … Arthritis Rheum 37:6:824-9 (1994)
58. Gibson RA: The effect of diets containing fish and fish oils on disease risk factors in humans. Aust N Z J Med 18:5:713-22 (1988)
59. Gogos CA, Ginopoulos P, Salsa B, Kalfarentzos F, et al.: Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely… Cancer 82:2:395-402 (1998)
60. Grimsgaard S, Bønaa KH, Hansen JB, Myhre ESP: Effects of highly purified eicosapentaenoic acid and docosahexaenoic acid on hemodynamics in humans. Am J Clin Nutr 68:52-59 (1998)
61. Grubb BP: Hypervitaminosis A following long-term use of high-dose fish oil supplements. Chest 97:5:1260 (1990)
62. Guallar E, Hennekens CH, Sacks FM, Willett WC, et al.: A prospective study of plasma fish oil levels and incidence of myocardial infarction in U.S. male physicians. J Am Coll Cardiol 25:2:387-94 (1995)
63. Haglund O, Wallin R, Luostarinen R, Saldeen T: Effects of a new fluid fish oil concentrate, ESKIMO-3, on triglycerides, cholesterol, fibrinogen and blood pressure. J Intern Med 227:5:347-53 (1990)
64. Haglund O, Luostarinen R, Wallin R, Wibell L, et al.: The effects of fish oil on triglycerides, cholesterol, fibrinogen and MDA in humans supplemented with vitamin E. J Nutr 121:2:165-9 (1991)
65. Harel Z, Biro FM, Kottenhahn RK, Rosenthal SL: Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents Am J Obstet Gynecol 174:1335-38 (1996).
66. Harris WS. n-3 Long-chain polyunsaturated fatty acids reduce risk of coronary heart disease death: extending the evidence to the elderly. Am J Clin Nutr 2003;77 279-280. http://www.ajcn.org/cgi/content/full/77/2/279
67. Hartmann G, Endres S: n-3 polyunsaturated fatty acids and human cytokine synthesis. In: Handbook of Essential Fatty Acid Biology (Yehu:Chapt. 5:103-113 (1997)
68. Heller A, Koch T, Schmeck J, van Ackern K: Lipid mediators in inflammatory disorders. Drugs 55:4:487-96 (1998)
69. Hibbeln JR: Fish consumption and major depression. Lancet 351:1213 (1998)
70. Hodge L, Salome CM, Peat JK, Haby MM, et al: Consumption of oily fish and childhood asthma risk see comments. Med J Aust 164:3:137-40 (1996)
71. Hogg RJ: A randomized, placebo-controlled, multicenter trial evaluating alternate-day prednisone and fish oil supplements. Am J Kidney Dis 26:5:792-6 (1995)
72. Hogg RJ: A randomized, placebo-controlled, multicenter trial evaluating alternate-day prednisone and fish oil supplements. Am J Kidney Dis 26:5:792-6 (1995)
73. Holm T, Andreassen AK, Aukrust P, Andersen K, et al.: Omega-3 fatty acids improve blood pressure control and preserve renal function in hypertensive heart transplant… Eur Heart J 22:5:428-36. (2001)
74. Holub B, Hunter E: Health effects of fish, fish oils. JAOCS 65:11 (Nov):1722-1726 (1988)
75. James MJ, McClelland LG: Dietary n-3 fatty acids and therapy for rheumatoid arthritis. Semin Arthritis Rheum 27:2:85-97 (1997)
76. James MJ, Gibson RA, Cleland LG: Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 71 (suppl):1 (s):343s-8s (2000)
77. Kaasgaard SG, Hølmer G, Høy CE, Behrens WA, et al.: Effects of dietary linseed oil and marine oil on lipid peroxidation in monkey liver in vivo and in vitro. Lipids 1992 27:10:740-5 (1992)
78. Kang JX, Leaf A: Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids. Am J Clin Nutr 71:1 S:202S-07S (2000)
79. Knapp HR, FitzGerald GA: The antihypertensive effects of fish oil. A controlled study of PUFA supplements in essential hypertension. N Engl J Med 320:16:1037-43 (1989)
80. Kromhout D: Fish consumption and sudden cardiac death (Editorial). JAMA 279:65-66 (1998)
81. Kremer JM, Jubiz W, Michalek A, Rynes RI, et al.: Fish-oil fatty acid supplementation in active rheumatoid arthritis. Ann Intern Med 106:4:497-503 (1987)
82. Kremer JM, Lawrence DA, Petrillo GF, Litts LL, et al.: Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Arthritis Rheum 38:8:1107-14 (1995)
83. Kremer JM: n-3 fatty acid supplements in rheumatoid arthritis. Am J Clin Nutr 71:1 Suppl:349S-51S (2000)
84. Kremer JM, Lawrence DA, Jubiz W, DiGiacomo R, et al.: Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. Arthritis Rheum 33:6:810-20 (1990)
85. Kelley DS, Bendich A: Essential nutrients and immunologic functions. Am J Clin Nutr 63:6:994S-996S (1996)
86. Kramer TR, Schoene N, Douglass LW, Judd JT, et al.: Increased vitamin E intake restores fish-oil-induced suppressed blastogenesis of mitogen-stimulated T lymphocytes. Am J Clin Nutr 54:5:896-902 (1991)
87. Kremer JM, Bigauoette J, Michalek AV, Timchalk MA, et al.: Effects of manipulation of dietary fatty acids on clinical manifestations of rheumatoid arthritis. Lancet 1:8422:184-7 (1985)
88. Kremer JM: Effects of modulation of inflammatory and immune parameters in patients with rheumatic and inflammatory disease receivin. Lipids 31 Suppl:S243-7 (1996)
89. Kremer JM: Clinical studies of omega-3 fatty acid supplementation in patients who have rheumatoid arthritis. Rheum Dis Clin North Am 17:2:391-402 (1991)
90. Kinsella JE: Dietary n-3 polyunsaturated fatty acids of fish oils, autoxidation ex vivo and peroxidation in vivo: implications. Adv Exp Med Biol 289:255-68 (1991)
91. Kudo N, Kawashima Y: Fish oil-feeding prevents perfluorooctanoic acid-induced fatty liver in mice. Toxicology & Applied Pharmacology 145:2:285-93 (1997)
92. Laganiere S, Yu BP, Fernandes G: Studies on membrane lipid peroxidation in omega-3 fatty acid-fed autoimmune mice: effect of vitamin E supplementatio. Adv Exp Med Biol 262:95-102 (1990)
93. Landmark K, Abdelnoor M, Urdal P, Kilhovd B, et al.: Use of fish oils appears to reduce infarct size as estimated from peak creatine kinase and lactate dehydrogenase activiti… Cardiology 89:2:94-102 (1998)
94. Lavine JB: Blood pressure and cholesterol in fish-eaters versus vegetarians (Letter) Lancet 348:1460 (1996)
95. Leaf A, Weber PC: Cardiovascular effects of n-3 fatty acids. New England Journal of Medicine 318:9:549-557 (1988)
96. Lee TH, Arm JP: Benefits from oily fish – may help in coronary artery disease and several inflammatory conditions. BMJ 297:1421-22 (1988)
97. Lund E, Bønaa KH: Reduced breast cancer mortality among fishermen’s wives in Norway. Cancer Causes Control 4:3:283-7 (1993)
98. Margolin G, Huster G, Glueck CJ, Speirs J, et al. Blood pressure lowering in elderly subjects: a double-blind crossover study of omega-3 and omega-6 fatty acids. Am J Clin Nutr 53:2:562-72 (1991)
99. Malasanos TH, Stacpoole PW Biological effects of omega-3 fatty acids in diabetes mellitus. Diabetes Care 14:12:1160-79 (1991)
100. Mayser P, Mrowietz U, Arenberger P, Bartak P, et al.: Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomi… Journal of the American Academy of Dermatology 38:4:539-47 (1998)
101. McCarty MF: Vascular heparan sulfates may limit the ability of leukocytes to penetrate the endothelial barrier–implication. Med Hypotheses 51:1:11-5 (1998)
102. Marchioli R, Tognoni G, GISSI Prevention Study, Valagussa F: Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction. Lancet 354:447-455 (1999)
103. Maurice PD, Allen BR, Barkley AS, Cockbill SR, et al.: The effects of dietary supplementation with fish oil in patients with psoriasis. Br J Dermatol 117:5:599-606 (1987)
104. Mori TA, Burke V, Puddey IB, Watts GF, et al.: Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL.. Am J Clin Nutr 71:5:1085-94 (2000)
105. Miller CC, Tang W, Ziboh VA, Fletcher MP: Dietary supplementation with ethyl ester concentrates of fish oil (n-3) and borage oil (n-6) polyunsaturated fatty ac. J Invest Dermatol 96:1:98-103 (1991)
106. Meydani M, Natiello F, Goldin B, Free N, et al.: Effect of long-term fish oil supplementation on vitamin E status and lipid peroxidation in women. J Nutr 121:4:484-91 (1991)
107. Navarro E, Esteve M, Olive A, Klaassen J, et al.: Abnormal fatty acid pattern in rheumatoid arthritis. A rationale for treatment with marine and botanical lipids. J Rheumatol 27:2:298-303 (2000)
108. Nordvik I, Myhr KM, Nyland H, Bjerve KS: Effect of dietary advice and n-3 supplementation in newly diagnosed MS patients. Acta Neurol Scand 102:3:143-9 (2000)
109. Nøding R, Schønberg SA, Krokan HE, Bjerve KS: Effects of polyunsaturated fatty acids and their n-6 hydroperoxides on growth of five malignant cell lines and th… Lipids 33:3:285-93 (1998)
110. O’Connor TP, Roebuck BD, Peterson F, Campbell TC: Effect of dietary intake of fish oil and fish protein on the development of L-azaserine-induced preneoplastic lesions. J Natl Cancer Inst 75:5:959-62 (1985)
111. Oomen CM, Feskens EJ, Rasanen L, Fidanza F, et al.: Fish consumption and coronary heart disease mortality in Finland, Italy, and The Netherlands. Am J Epidemiol 151:10:999-1006 (2000)
112. Olsen SF, Sørensen JD, Secher NJ, Hedegaard M, et al.: Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration. Lancet 339:8800:1003-7 (1992)
113. Olsen SF, Secher NJ, Tabor A, Weber T, et al.: Randomised clinical trials of fish oil supplementation in high risk pregnancies. Fish Oil Trials In Pregnancy (FOTIP). BJOG 107:3:382-95 (2000)
114. Opstvedt J: Fish lipids: more than n-3 fatty acids? Med Hypotheses 48:6:481-3 (1997)
115. Rozenn N Lemaitre, Irena B King, Dariush Mozaffarian, Lewis H Kuller, Russell P Tracy, and David S Siscovick. n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr 2003;77 319-325. http://www.ajcn.org/cgi/content/abstract/77/2/319
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Joseph E. Pizzorno Jr., Michael T. Murrey & Melvyn R. Werbach.