Category: Vitamins in general

Vitamin B9, Folic acid, Folate, Research references

Admin

January 1999

1. Alpert JE, Fava, M. Nutrition and depression. The role of folate. Nutr Rev 55: 145-149, 1997.
2. Bailey LB, Wagner PA, Davis CG, Dinning JS. Food frequency related to folacin status in adolescents. J Am Diet Assoc 84: 801-804, 1984.
3. Baker H, Jaslow SP, Frank O. Severe impairment of dietary folate utilization in the elderly. J Am Geriatr Soc 26: 218-221, 1978.
4. Bates CJ, Fleming M, Paul AA et al. Folate status and its relation to vitamin C in healthy elderly men and women. Age Aging 9: 241-248, 1980.
5. Bendich A, Cohen M. Nutrition and immunology. New York: Alan R. Liss. p 101-123, 1988.
6. Botez MI, Botez T, Léveillé J, et al. Neuropsychological correlates of folic acid deficiency: Facts and hypotheses, in MI Botez, EH Reynolds, Eds. Folic Acid in Neurology, Psychiatry, and Internal Medicine. New York, Raven Press, 435-461, 1979.
7. Brattstrom LE, Hultberg BL, Hardebo JE. Folic acid responsive postmenopausal homocysteinemia. Metabolism 34: 1073-1077, 1987.
8. Brattstrom LE, Israelsson B, Jeppsson JO, Hultberg BL. Folic acid – an innocuous means to reduce plasma homocysteine. Scand J Clin Lab Invest 48: 3; 215-221, 1988.
9. Brattström L et al. Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment. Atherosclerosis 81:1:51-60, 1990.
10. Briggs RM. Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans. Clin Plast Surg 1976; 3: 647-652, 1976.
11. Butterworth CE, Tamura T. Folic acid safety and toxicity. A brief review. Am J Clin Nutr 50: 353-358, 1989.
12. Center for Disease Control. Knowledge about folic acid and use of multivitamins containing folic acid among reproductive-aged women. Morbidity Mortality Weekly Report 45: 793-795, 1996.
13. Center for Disease Control. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. Morbidity Mortality Weekly Report 41: RR-14, 1996.
14. Clark AJ, Mossholder S, Gates R. Folacin status in adolescent females. Am J Clin Nutr 1987; 46: 302-306.
15. Dalery K et al. Homocysteine and coronary artery disease in French Canadian subjects: Relation with vitamins B12, B6, pyridoxal phosphate and folate. Am J Cardiol 75:1107-11, 1995.
16. Deller DJ et al. Folic acid deficiency in rheumatoid arthritis. Relation of levels of serum folic acid activities to treatment with phenylbutazone. Br Med J i: 765-7, 1966.
17. Flynn MA, Irvin W, Krause G. The effect of folate and cobalamin on osteoarthritic hands. J Am Coll Nutr 13; 4: 351-6, 1994.
18. Gaby SK, Bendich A. Vitamin intake and health: A scientific review. New York: Marcel Dekker. p 175-188, 1991.
19. Gough KR et al. Folic acid deficiency in rheumatoid arthritis. Br Med J i: 212-17, 1964.
20. Halsted CH, Reisenauer AM, Romero JJ, et al. Jejunal perfusion of simple and conjugated folates in celiac sprue. J Clin Invest 59: 933-40, 1977.
21. Hjelt K, Krasilnikoff PA. The impact of gluten on haematolgical status, dietary intakes of haemopoietic nutrients and vitamin B12 and folic acid absorption in children with coeliac disease. Acta Paediatr Scand 79; (10):911-19, 1990.
22. Huber AM, Wallins LL, DeRusso P. Folate nutriture in pregnancy. J Am Diet Assoc 88: 791-814, 1988.
23. Jacques P, Bostom A, Williams R, et al. Relation between folate status, a common mutation in methylene tetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93; 1: 7-9, 1996.
24. Kang SS, Wong PWK, Norusis M. Homocysteinemia due to folate deficiency. Metabolism 36: 458-462, 1987.
25. Laurence KM, James N, Miller MH et al. Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. Br Med J 282: 1509-1511, 1981.
26. Milunsky A, Jick H, Jick SS, Bruell CL, MacLaughlin DS, Rothman KJ, Willette W. Multivitamin/folic acid supplementation in early pregnancy reduces the pr-reviewence of neural tube defects. J Am Med Assoc 262: 2847-2852, 1989.
27. Modesto C, Castro L. Folinic acid supplementation in patients with juvenile rheumatoid arthritis treated with methotrexate. J Rheumatol 23; (2): 403-4, 1996.
28. Morgan SI, Alarcon GS, Krumdieck CL. Folic acid supplementation during methotrexate therapy: It makes sense. Editorial. J Rheumatol 20; (6): 929-30, 1993.
29. Morgan SL, Baggott JE, Vaughn WH, et al. Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis: a double-blind, placebo-controlled trial. Ann Intern Med 121: 833-41, 1994.
30. Murray, MT. reviewuating the many benefits of folic acid. Am J Natural Med 3: 8-11, 1996.
31. Omer A, Mowat AG. Nature of anaemia in rheumatoid arthritis. IX. Folate metabolism in patients with rheumatoid arthritis. Ann Rheum Dis 27: 414-24, 1968.
32. Preuss HG. CRC Handbook series in nutrition and food. Section F: Nutntional disorders, vol. 1. Boca Raton, FL: CRC Press. p 61-62, 1978.
33. Selhub, J, Rosenberg, IH. Folic acid. In: Present knowledge in nutrition. 7th edn. Washington DC: International Life Sciences Press. p 206-219, 1996.
34. Smithells RW, Nevin NC, Seller MJ et al. Further experience of vitamin supplementation for prevention of neural tube defect recurrences. Lancet 1: 1027-1031, 1983.
35. Ubbink JB, Vermaak WJH, van der Merwe A, Becker PJ. Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 57:47-53, 1993.
36. Ventura A, bouquet F, Sartorelli C, et al. Coeliac disease, folic acid deficiency and epilepsy with cerebral calcifications. Acta Paeditr Scand 80; (5):559-62, 1991.
37. Verhoef P, Stampfer MJ, Buring JE, et al. Homocysteine metabolism and risk of myocardial infarction: Relation with vitamin B6, B12, and folate. Am J Epidemiol 143:9:845-59, 1996.
38. Weisburger JH. Nutritional approach to cancer prevention with emphasis on vitamins, antioxidants, and carotenoids. Am J Clin Nutr 53: S226-S237, 1991.

 

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Joseph E. Pizzorno Jr., Michael T. Murrey & Melvyn R. Werbach.

Vitamin B12, Research references

Admin

January 1999

1. Allen, LH, Casterline J. Vitamin Bl2 deficiency in elderly individuals. diagnosis and requirements. Am J Clin Nutr 60: 12-14, 1994.
2. Baker H et al. Plasma vitamin B12 titres as indicators of disease severity and mortality of patients with alcoholic hepatitis. Alcohol Alcoholism 22; (1):15, 1987.
3. Brinton LA, Gridley G, Hrubec A et al. Cancer risk following pernicious anemia. Br J Cancer 59: 810-813, 1989.
4. Campbell RE, Pruitt FW. Vitamin B12 in the treatment of viral hepatitis. Am J Med Sci 224:252, 1952.
5. Campbell RE, Pruitt FW. The effect of vitamin B12 and folic acid in the treatment of viral hepatitis. Am J Med Sci 229:8-15, 1955.
6. Carethers M. Diagnosing vitamin Bl2 deficiency, a common geriatric disorder. Geriatrics 43: 89-112, 1988.
7. Chu RC, Hall CA. The total serum homocysteine as an indicator of vitamin Bl2 and folate status. Am J Clin Pathol 90: 446-449, 1988.
8. Dalery K et al. Homocysteine and coronary artery disease in French Canadian subjects: Relation with vitamins B12, B6, pyridoxal phosphate and folate. Am J Cardiol 75:1107-11, 1995.
9. Davidson S. The Use of Vitamin B12 in the Treatment of Diabetic Neuropathy. J Flor Med Assoc 15: 717-20, 1954.
10. Doscherholmen A, Swaim WR. Impaired assimilation of egg 57 Co vitamin Bl2 in patients with hypochlorhydria and achlorhydria and after gastric resection. Gastroenterol 1973; 64: 913-919.
11. Ellis FR, Nasser S. A pilot study of vitamin B12 in the treatment of Tiredness. Br J Nutr 30: 277-83, 1973.
12. Gaby SK, Bendich A. Vitamin intake and health: A scientific review. New York: Marcel Dekker. p 193-197, 1991.
13. Gaby AR. The story of vitamin B12: Is vitamin B12 a panacea or placebo? Nutrition & Healing 2; 7, July, 1995.
14. Goodman KI, Salt WB 2nd. Vitamin B12 deficiency. Important new concepts in recognition. Postgrad Med 88; 3: 147-50, 153-8, 1990.
15. Gupta AK, Mital H.S. Cyanocobalamin (vitamin B12) in the management of Herpes Zoster. Indian Pract 20; (7):457-9, 1967.
16. Harriman GR et al. Vitamin B12 malabsorption in patients with acquired immunodeficiency syndrome. Arch Intern Med 149; (9):2039-41, 1989.
17. Heyblon R. Vitamin B12 in herpes zoster. Abstract. JAMA 146:1338, 1951.
18. Herbert, V. Vitamin B-l2. In: Present knowledge in nutrition. 7th edn. Washington DC: International Life Sciences Press. 1996: p 191-205.
19. Heimburger DC, Alexander CB, Birch R, Bailey WC, Krumdieck CL. Improvement in bronchial squamous metaplasia in smokers treated with folate and vitamin Bl2. J Am Mcd Assoc 259: 1525-1530, 1988.
20. Herbert V. B12 deficiency and AIDS. Letter. JAMA 260; (19):2837, 1988.
21. Herzlich BC et al. Synergy of inhibition of DNA synthesis in human bone marrow by azidothymidine plus deficiency of folate and/or vitamin B12? Am J Hematology 33:177-83, 1990.
22. Hjelt K, Krasilnikoff PA. The impact of gluten on haematolgical status, dietary intakes of haemopoietic nutrients and vitamin B12 and folic acid absorption in children with coeliac disease. Acta Paediatr Scand 79; (10):911-19, 1990.
23. Inada M, Toyoshima M, Kameyama M. Brain content of cobalamin and its binders in elderly subjects. J Nutr Sci Vitaminol 28: 351-357, 1982.
24. Kokkonen J, Similä S. Gastric function and absorption of vitamin B12 in children with celiac disease. Eur J Pediatr 132; (2):71-5, 1979.
25. Lederle FA. Oral cobalamin for pernicious anemia. Medicine’s best kept secret? JAMA. 265: 94-95, 1991.
26. Nilsson-Ehle H, Landahl S, Lindstealt G et al. Low serum cobalamin levels in population study of 70- and 75-year-old subjects. Dig Dis Sci 34: 716-723, 1989.
27. Olszewski AJ, Szostak WB, McCully KS. Plasma glucosamine and galactosamine in ischemic heart disease. Atherosclerosis 75:1-6, 1989.
28. Omaye ST. Nutritional and toxicological aspects of food safety. New York: Plenum Press. p 169-203, 1984.
29. Richardson LR, Brock R. Studies of reproduction in rats using large doses of vitamin Bl2 and highly purified soybean proteins. J Nutr 1956; 58: 135-145.
30. Robertson KR et al. Vitamin B12 Deficiency and Nervous System Disease in HIV Infection, Arch Neurol 50:807-11, 1993.
31. Rule SAJ et al. Serum vitamin B12 and Transcobalamin levels in early HIV Disease. Am J Hematol 47:167-71, 1994.
32. Shemesh Z et al. Vitamin B12 deficiency in patients with chronic tinnitus and noise-induced hearing loss. Am J Otolaryngol 14; (2):94-9, 1993.
33. Shils ME, Young VR. Modem Nutrition in Health and Disease. 7th edn. Lea and Febiger. p 401-404, 1988.
34. Tang AM, Graham NM, Chandra RK, Saah AJ. Low Serum Vitamin B-12 concentrations are associated with Faster Human Immunodeficiency Virus type 1 (HIV-1) disease progression. J Nutr 127:345-51, 1997.
35. Ubbink JB, Vermaak WJH, van der Merwe A, Becker PJ. Vitamin B-12, vitamin B-6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 57: 47-53, 1993.
36. Uchizyama M et al. Effects of vitamin B12 on human circadian body temperature rhythm. Neurosci Lett 192: 1-4, 1995.
37. Verhoef P, Stampfer MJ, Buring JE, et al. Homocysteine metabolism and risk of myocardial infarction: Relation with vitamin B6, B12, and folate. Am J Epidemiol 143:9:845-59, 1996.
38. Wright J.V. Treatment of childhood asthma with parenteral vitamin B12, gastric reacidification, and attention to food allergy, magnesium and pyridoxine: Three case reports with background and an integrated hypothesis. J Nutr Med 1: 277-82, 1990.

 

Sources
Joseph E. Pizzorno Jr., Michael T. Murrey & Melvyn R. Werbach.

Vitamin C, Research references

Admin

January1999

1. Anderson R, Oosthuizen R, Maritz R et al. Effects of increasing weekly doses of ascorbate on certain cellular and humoral immune functions in normal volunteers. Am J Clin Nutr 33: 71-76, 1980.
2. Atkins GL et al. Quantitative aspects of ascorbic acid metabolism in man. J Biol Chem 239:2975-80, 1964.
3. Baetgen D. Results of the treatment of epidemic hepatitis in children with high doses of ascorbic acid in the years 1957 – 1958. Medizinische Monatschrift 15:30-36, 1961 (in German).
4. Baird IM et al. The effects of ascorbic acid and flavonoids on the occurrence of symptoms normally associated with the common cold. Am J Clin Nutr 32: 1686-90, 1979.
5. Baur H, Staub H. Treatment of hepatitis with infusions of ascorbic acid: Comparison with othertherapies. Abstract. JAMA 156; (5): 565, 1954.
6. Bendich A, Langseth L. The health effects of vitamin C supplementation. A review J Am Col Nutr 14: 124-136, 1995.
7. Belfield, WO, Stone, I. Megascorbic prophylaxis and megascorbic therapy: A new orthomolecular modality in veterinary medicine. Journal of the International Academy of Preventive Medicine, 2:10-26, 1975.
8. Bjelke E. Epidemiologic studies of cancer of the stomach, colon and rectum; with special emphasis on diet. Scand J Gastroenterol 9: 1-235S, 1974.
9. Block G. Vitamin C and cancer prevention. The epidemiologic evidence. Am J Clin Nutr 53: 270S-282S, 1991.
10. Blondin J et al. Prevention of eye lens protein damage by dietary vitamin C. Fed Proc 45:478, 1986.
11. Bordia A et al. Effect of vitamin C on platelet adhesiveness and platelet aggregation in coronary artery disease patients. Clin Cardiol 810:552-4, 1985.
12. Bouton SM Jr. Vitamin C and the aging eye. Arch Intern Med 63:930-45, 1939.
13. Brighthope I. AIDS – Remissions using nutrient therapies and megadose intravenous ascorbate. Int Clin Nutr Rev 7; (2):53-75, 1987.
14. Bulpitt CJ. Vitamin C and blodd pressure. J of Hypertension 12; 1071-1075, 1990.
15. Buzina R, Suboticanec K. Vitamin C and physical working capacity. Int Z VitamErnahrungsforsch (Bern) 27: 157-66, 1985; Suboticanec-Buzina K et al. Vitamin C status and physical working capacity in adolescents. Int J Vitam Min Res 54; 1: 55-60, 1984.
16. Calabrese EJ. Does exposure to environmental pollutants increase the need for vitamin C? J Environ Pathol Toxicol Oncol 1985, 5: 81-90, 1985.
17. Calleja HB, Brooks RH. Acute hepatitis treated with high doses of vitamin C. Ohio State Med J 56:821-3, 1960.
18. Cameron, E, Pauling, L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci. USA, 73:3685-3689, 1976.
19. Cameron, E, Pauling, L. The orthomolecular treatment of cancer: Rereviewuation of prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci. USA, 75:4538-4542, 1978.
20. Cameron, E, Pauling, L. Cancer and Vitamin C. The Linus Pauling Institute for Science and Medicine, Menlo Park, 1979.
21. Campbell, GD Jr., Steinberg, MH and Bower, JD. Ascorbic acid induced hemolysis in G-6-PD deficiency. Ann. Int. Med. 82:810, 1975.
22. Carr AB, Einstein R, Lai LYC, et al. Vitamin C and the common cold: Using identical twins as controls. Med J Aust 2: 8: 411-12, 1981.
23. Cathcart, RF. Clinical trial of vitamin C. Medical Tribune, June 25, 1975.
24. Cathcart, RF. Clinical use of large doses of ascorbic acid. Presented at the annual meeting of the California Orthomolecular Medical Society, San Francisco, February 19, 1976.
25. Cathcart, RF. Vitamin C as a detoxifying agent. Presented at the annual meeting of the Orthomolecular Medical Society, San Francisco, January 21, 1978.
26. Cathcart, RF. Vitamin C – The missing stress hormone. Presented at the annual meeting of the Orthomolecular Medical Society, San Francisco, March 3, 1979.
27. Cathcart, RF. The method of determining proper doses of vitamin C for the treatment of disease by titrating to bowel tolerance. J. Orthomolecular Psychiatry, 10:125-132, 1981.
28. Cathcart RF III. Vitamin C in the treatment of acquired immune deficiency syndrome (AIDS). Med Hypotheses 14; 4:423-33, 1984.
29. Cathcart RF 3rd. Glutathione and HIV infection. Letter. Lancet i:235, 1990; Cathcart RF 3rd. Vitamin C in the treatment of acquired immune deficiency syndrome (AIDS). Med Hypotheses 14; (4):423-33, 1984.
30. Cathcart, RF. The third face of vitamin C. J Orthomol Med 7: 197-200, 1992.
31. Chakrabarty S, Nandi A, Mukhopadhyay C, et al. Protective role of ascorbic acid against lipid peroxidation and myocardial injury. Mol Cell Biochem 111:41-7, 1992.
32. Chamiec T et al. Effects of antioxidant vitamins C and E on signal-averaged electrocardiogram and acute myocardial infarction. Am J Cardiol 77:237-41, 1996.
33. Chandra DB, Varma R, Ahmad S et al. Vitamin C in the human aqueous humor and cataracts. Int J Vit Nutr Res 56: 165 168, 1986.
34. Chandra DB et al. Vitamin C in the human aqueous humor and cataracts. Int J Vitam Nutr Res 56:165-9, 1986.
35. Cheraskin E, Ringsdorf WM Jr, Michael DW et al. Daily vitamin C consumption and reported respiratory findings. Int J Vit Nutr Res 43: 42-55, 1973.
36. Cheraskin E, Ringsdorf WM Jr. Vitamin C and chronologic versus bone age. J Tenn Dent Assoc  57: 177-178, 1974.
37. Cheraskin E, Ringsdorf WM Jr, Medford FH. Daily vitamin C consumption and fatigability. J Am Geriatr Soc 24; (3): 136-7, 1976.
38. Cheraskin E, Ringsdorf WM Jr, Medford FH. The ‘ideal’ daily vitamin C intake. J Med Assoc State Alabama  46: 39-40, 1977.
39. Choi ESK et al. Correlation of plasma ascorbic acid with cardiovascular risk factors. Am J Clin Nutr 51:511, 1990.
40. Cheraskin E, Ringsdorf WM Jr, Sisley EL. The vitamin C connection. New York: Harper & Row. p 1-279, 1983.
41. Cook JD, Watson SS, Simpson KM et al. The effect of high ascorbic acid supplementation on body iron stores. Blood 64: 721-726, 1984.
42. Cousins, N. Anatomy of an Illness as Perceived by the Patient. W.W. Norton & Company, New York, 1979.
43. Cunningham J. Reduced Mononuclear Leukocyte Ascorbic Acid Content in Adults with Insulin-Dependent Diabetes Mellitus Consuming Adequate Dietary Vitamin C. Metabolism 40: 146-49, 1991.
44. Cunningham JJ, Mearkle PL and Brown RG. Vitamin C: An Aldose Reductase Inhibitor that Normalizes Erythrocyte Sorbitol in Insulin-Dependent Diabetes Mellitus. J Am Coll Nutr 4: 344-50, 1994.
45. Curhan GC, Willett WC, Rimm EB, Stampfer MJ. A prospective study of the intake of vitamins C and B6, and the risk of kidney stones in men. J Urol 155:61847-51, 1996.
46. Dallal GE et al. Ascorbic acid, HDL cholesterol, and apolipoprotein A-I in an elderly Chinese population in Boston. J Am Coll Nutr 8;1:69-74, 1989.
47. Davie Sj, Gould BJ and Yudkin JS. Effect of Vitamin C on Glycosylation of Proteins. Diabetes 41: 167-73, 1992.
48. Dawson EB. Relationship between ascorbic acid and male fertility. World Review of Nutrition and Dietetics 62; 1-26, 1990.
49. Devamanoharan P et al. Prevention of selenite cataract by vitamin C. Exp Eye Res 52:563-8, 1991.
50. Dobson HM et al. The effect of ascorbic acid on the seasonal variations in serum cholesterol levels. Scot Med J 293:176-82, 1984.
51. Eaton SB, Shostak M, Konner M. The paleolithic prescription. New York: Harper & Row. p 82,130-131, 1988.
52. Emstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidem 3: 194-202, 1992.
53. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology 3:3:194-202, 1992.
54. Erden F, Gulenc S, Torun M et al. Ascorbic acid effect on some lipid fractions in human beings. Acta Vitaminol Enzymol 7: 131-138, 1985.
55. Eriksson J, Kohvakka A. Magnesium and ascorbic acid supplementation in diabetes mellitus. Ann Nutr Metab 394:217-23, 1995.
56. Esk C et al. Correlation of plasma ascorbic acid with cardiovascular risk factors. Clin Res 38:A747, 1990.
57. Fontham ET, Pickle LW, Haenszel W et al. Dietary vitamins A and C and lung cancer risk in Louisiana. Cancer 62: 2267-2273, 1988.
58. Fraga CG. Ascorbic acid protects against endogeneous oxidative DNA damage in human sperm. Proceedings of the National Academy of Sciences 88; 11003-6, 1991.
59. Freudenheim JL, Johnson NE, Smith EL. Relationships between usual nutrient intake and bone-mineral content of women 35-65 years of age. longitudinal and cross-sectional analysis. Am J Clin Nutr 44: 863-876, 1986.
60. Gaby SK, Singh VN. Vitamin intake and health: A scientific review. New York: Marcel Dekker. p 103-161, 1991.
61. Gatto LM, Hallen GK, Brown AJ, Samman S. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutr 152:154-8, 1996.
62. Gey KF. Scientific evidence for dietary targets in europe bibliotheca nutr deta, vol. 37. Basil: Karger, 1986.
63. Gey KF, Stahelin HB, Eichholzer M. Poor plasma status of carotene and vitamin C is associated with higher mortality from ischemic heart disease and stroke: Basel Prospective Study. Clin Invest 71:3-6, 1993.
64. Ginter E. Cholesterol: Vitamin C controls its transformation to bile acids. Science 179; (74):702-4, 1973.
65. Ghosh J, Das S. reviewuation of vitamin A and C status in normal and malignant conditions and their possible role in cancer prevention. Jpn J Cancer Res 76: 1174-1178, 1985.
66. Ginter E, Cerna O, Budlovsky J et al. Effect of ascorbic acid on plasma cholesterol in humans in a long-term experiment. Int J Vit Nutri Res 47: 123-134, 1977.
67. Ginter E et al. Vitamin C in the control of hypercholesterolemia in man. Int J Vitam Nutr Res Suppl 23:137-52, 1982.
68. Greco AM, Gentile M, DiFilippo O et al. Study of blood vitamin C in lung and bladder cancer patients before and after treatment with ascorbic acid. A preliminary report. Acta Vitaminol Enzymol 4: 155-162, 1982.
69. Greenwood, J. Optimum vitamin C intake as a factor in the preservation of disc integrity. Medical Annals of the District of Columbia, 33:274-276, 1964.
70. Gustafsson U et al. The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: Prolongation of the nucleation time. Eur J Clin Invest 27:387-91, 1997.
71. Hallberg L, Rossander L. Absorption of iron from Western-type lunch and dinner meals. Am J Clin Nutr 35: 502-509, 1982.
72. Hallfrisch J et al. High plasma vitamin C associated with increased plasma HDL- and HDL 2 -cholesterol. Clin Res 39: A203, 1991.
73. Hallfrisch J, Singh VN, Muller DC, et al. High plasma vitamin C associated with high plasma HDL-and HDL2 cholesterol. Am J Clin Nutr 60:100-5, 1994.
74. Harakeh S, Jariwalla RJ, Pauling L. Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells. Proc Natl Acad Sci USA 87; (18):7245-9, 1990.
75. Harakeh S, Jariwalla RJ. Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chronically HIV-infected cells. Am J Clin Nutr 54:1231S-5S, 1991.
76. Harakeh S, Jariwalla RJ. Ascorbate Effect on Cytokine Stimulation of HIV Production, Nutrition 11, Suppl. 5: 684-7, 1995.
77. Herbaczynska-Cedro K, Klosiewicz-Wasek B, Cedro K, et al. Supplementation with vitamins C and E suppresses leukocyte oxygen free radical production in patients with myocardial infarction. Eur Heart J 16:1044-9, 1995.
78. Hemilä H. Vitamin C and the common cold. Br J Nutr 67:3-16, 1992.
79. Hemilä H. Vitamin C and plasma cholesterol. Crit Rev Food Sci Nutr 32: 33-57, 1992.
80. Hemilä H. Does vitamin C alleviate symptoms of the common cold? – a review of current evidence. Scand J Infect Dis 26:1-6, 1994.
81. Hemilä H, Herman ZS. Vitamin C and the common cold: A retrospective analysis of Chalmers’ review. J Am Coll Nutr14; (2):116-23, 1995.
82. Hemilä H. Vitamin C supplementation and common cold symptoms: Problems with inaccurate reviews. Nutrition 12; (11-1):804-9, 1996.
83. Hemilä H. Vitamin C and common cold incidence: A review of studies with subjects under heavy physical stress. Int J Sports Med 17; 5: 370-83, 1996.
84. Hemilä H. Vitamin C, the placebo effect, and the common cold: a case study of how preconceptions influence the analysis of results. J Clin Epidemiol 49; 10: 1079-84, 1996.
85. Hemilä H. Vitamin C intake and susceptibility to the common cold. Br J Nutr 77:1-14, 1997.
86. Henson DE. Ascorbic acid: Biologic functions and relation to cancer. J of Nat Cancer Inst 83; 8; 547-550, 1991.
87. Horsey J, Livesley B, Dickerson JW. Ischemic heart disease and aged patients: Effects of ascorbic acid on lipoproteins. J Hum Nutr 35:1:53-8, 1981.
88. Hovi T et al. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antivi Res 27; (3):263-70, 1995.
89. Howard PA and Meyers DG, Effect of Vitamin C on Plasma Lipids Pharmacother 29; 1129-36, 1995.
90. Hume R, Weyers E. Changes in leucocyte ascorbic acid during the common cold. Scot Med J 18:3-7, 1973.
91. Jacques PF et al. Ascorbic acid, HDL, and total plasma cholesterol in the elderly. J Am Coll Nutr 6;2:169-74, 1987.
92. Jacques PF. Effects of vitamin C on high-density lipoprotein cholesterol and blood pressure. J Am Coll Nutr 11;2:139-44, 1992.
93. Jacques PF et al., Ascorbic Acid and Plasma Lipids, Epidemiol 5; 19-26, 1994.
94. Jacques PF, Sulsky SI, Perrone GA, Schaefer EJ. Ascorbic acid and plasma lipids. Epidemiology 5:19-24, 1994.
95. Jacques PF, Sulsky SI, Perrone GE, et al. Effect of vitamin C supplementation on lipoprotein cholesterol, apolipoprotein, and triglyceride concentrations. Ann Epidemiol 51:52-9, 1995.
96. Jenkins SA. Vitamin C and gallstone formation: A preliminary report. Experientia 33:1616-17, 1977.
97. Jenkins SA. Biliary lipids, bile acids and gallstone formation in hypovitaminotic C guinea-pigs. Br J Nutr 40:317-22, 1978.
98. Jenkins SA. Vitamin C status, serum cholesterol levels and bile composition in the pregnant guinea-pig. Br J Nutr 43:1:95-100, 1980.
99. Jialal I, Vega Gl, Grundy SM. Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein. Atherosclerosis 82:185-91, 1990.
100. Johnston CS, Luo B. Comparison of the absorption and excretion of three commercially available sources of vitamin C. J Am Dietetic Assoc 94: 779-781, 1994.
101. Kennes B, Dumont 1, Brohee D et al. Effect of vitamin C supplements in cell-mediated immunity in old people. Gerontology 29: 310, 1983.
102. Khaw K-T, et al. Lancet, Vol. 357; 9257: p. 657-663, 2001
103. Khaw K-T, Woodhouse P. Interrelation of vitamin C, infection, hemostatic factors and cardiovascular disease. BMJ 310:1559-63, 1995.
104. Kinsman RA, Hood J. Some behavioral effects of ascorbic acid deficiency. Am J Clin Nutr 24; (4): 455-64, 1971.
105. Klenner, FR. Virus pneumonia and its treatment with vitamin C. J. South. Med. and Surg., 110:60-63, 1948.
106. Klenner, FR. The treatment of poliomyelitis and other viral diseases with vitamin C. J. South. Med. and Surg., 111:210-214, 1949.
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Manganese, Research references

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Joseph E. Pizzorno Jr., Michael T. Murrey & Melvyn R. Werbach.