A stool with one leg

February 21, 2021

As previously quoted, they wrote in the Lancet (1) December 20th that in the future everything should be done to prevent and vaccinate and find methods for the treatment of Covid-19, and the Vitality Council can’t agree more that this stool should rest on three legs.

But the Danish government has not agreed to that. Since March 2020, it has focused on vaccines and only vaccines. – A one-legged stool.

Not only has the Government and the state media focused unilaterally on vaccines, but they have also actively censored information on both prevention and treatment. The government media has also been obediently accompanied by microphone holders from the major social and print media. It has been irrelevant to the censorship whether this information was sufficiently well documented.

Prevention

In the previous many newsletters, the Vitality Council has primarily advised on prevention in terms of keeping the immune system intact.

In our modern way of life with easy and fast industrial food of poor quality, improper preparation and overeating of carbohydrates, there is a great risk that our immune system will run out of essential nutrients. I have reviewed this topic again and again and will not bore you with this at this time.

But I will try to give a simple model for understanding the functioning of the immune system. This is because it is absolutely essential in prevention against Covid-19 and all sorts of other infections.

The immune system has a myriad of different cells to work with, and it’s pretty complicated, but let’s try a Pixie model; -a mousetrap:
There are two main systems, a so-called “innate” (non-specific) immune system, which works all the time, and an “adaptive” (specialized) immune system, which is adjusted by infection. The innate system attacks just about everything when, for example, a virus penetrates the body, but first the adaptive needs to get familiar with the new virus, adjust and activate the so-called T cells for attack, and teach the memory cells to remember for the next time how these virus are best attacked (antibodies).

Back to the mousetrap.

In the loft with all the mice (virus in the environment) we put a box (the body), with a small hole in the side (the innate immune system), and inside the box we put a couple of mousetraps (the adaptive immune system).

If we lack proper nutrition, vitamin D, selenium, vitamin C and magnesium, then the hole in the box is very large (the innate immune system fails). Then many mice can enter the box at once, and the traps (the adaptive immune system) do not have the capacity to snatch many mice. – Especially not if there is a lack of vitamin D, which is necessary to activate the T cells (2).

If, on the other hand, we get enough of the above nutrients, then we only have a small hole in the box (a good innate immune system), and then only a few mice enter the box (the body) at a time, and the adaptive immune system (the traps) can snatch them one by one.
Remember the Danish Minister of Health showing a graph with red and green curves some time ago.
If too many come too fast, then the hospital system would collapse.
The same way with our immune system.

If it is intact, the innate immune system will make sure to moderate the load so that the adaptive defense can have time to get to know the enemy and calibrate its cannons accordingly. Hereby we avoid the overload that results in the so-called cytokine storm, which is the start of all the accidents.

That is why it is so important to provide proper nutrition and supplement with vitamin D, vitamin C, selenium and magnesium.
And remember in the dark winter: Vitamin D in the blood should rise to 30-50 ng/ml (75-125 nmol /L.)
If you can’t get the blood sample taken locally, there are several excellent options for home testing i Denmark (3,4).

Treatment

Often you see pseudo-science, where vitamins and minerals are used as treatment after disease outbreaks, and even often in relatively small doses. It is pointless and only suitable to show that it does not work. These nutrients are for prevention.
An exception, however, is Vitamin C in high doses given intravenously under medical supervision.

There is only scant evidence here at the Covid-19 pandemic (5), but previously there is ample evidence of an effect on viral infections, as mentioned in the newsletter May 20th 2020.

There have been numerous experiments with hydroxychloroquine, which, however, have yielded quite varying results, and research into it is unfortunately largely discontinued.

Ivermectin is a remedy against scabies and certain parasites, and reportedly also has an effect on Covid-19 (6). The Indian health authorities have approved a treatment with Ivermectin, Doxycycline and zinc.
Ivermectin costs about 100 times as much as hydroxychloroquine, so it will probably never be the big success.
One week ago, Israeli researchers published (7) a preliminary result of treatment with inhalation of CD24 exosomes in 30 hospitalized moderately to severely ill Covid-19 patients. The 29 recovered in 3-5 days, the last one also recovered, but after more than 5 days. It should be a cheap method without side effects, so it sounds promising. CD24 exosomes are proteins that, like vitamin D, control T cell activation and can attenuate the cytokine storm.
We are anxiously awaiting news from the Israeli researchers.

What now?

After all, health authorities and the government are on thin ice right now, unless they manage to be saved by the globally declining infection rates and death rates.
You vaccinate and vaccinate, but to no avail on the closure of the society. The function of the vaccine is primarily to alleviate the disease in the vaccinated person.
Even though we have been vaccinated, we can still be infected and pass it on to others, because the virus is still there. Therefore, even the vaccinated must continue with face masks, despite the poor evidence of the effect of the hated face masks.
On top of this, there are still new mutations. Currently the English with increased infection of children, which we see in Kolding these days, but on the horizon lurks the South African and two different Brazilian varieties, which are even less sensitive to the antibodies we have received from previous infection and from vaccination.
Well, then the vaccine just has to be adjusted, and then the population just has to be vaccinated again.
Okay. -How many times? So far, in 2 months we have only vaccinated 3% of the population. So good luck with the task if it all has to start all over again.
It seems like a Sisyphean task if the Government will continue to focus only on the one-legged stool.
As a solution to this chaos, the Government is now proposing a wild testing strategy, where we will be tested twice a week next year. This will cost just as much as the overall healthcare system, and one does not have to be a nuclear physicist to figure out that this will massively affect all other diagnoses in the healthcare system.
And the virus will not disappear either due to this.
It’s a bit like setting up photo traps to detect an army of soldiers invading the country. No defense, just registration while the invasion rumbles towards the defenseless population.
When the hopelessness of this strategy eventually dawns on the Government, there is hope that the one-legged stool will be given two more legs, namely prevention and treatment.
Then every single person can be informed about the possibility of defending themselves against Covid-19.
Only then will the disease become so mild that it resembles a common flu, by which we can drop the hated face masks and the lockdown of society.

May we ask for the three-stringed strategy as soon as possible thank you.

A stool with one leg is doomed to tip over.
A stool with three legs does not tip over.
No matter how uneven the surface is, it will not even tilt.

Take care of yourself and others.

Claus Hancke MD
Specialist in general medicine

References

  1. Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study. Piroth L et al, Dec.2020, Lancet. https://www.sciencedirect.com/science/article/pii/S2213260020305270
  2. Geisler C, Ødum N et al. 2010, Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nature Immunology 2010;11:344-349.
    https://www.nature.com/articles/ni.1851
  3. https://www.webapoteket.dk/saar-og-sygepleje/selvtest/quicktest-d-vitamin-p-222465
  4. https://www.cerascreen.dk/products/test-for-d-vitamin
  5. Alberto Boretti, Bimal Krishna Banik (2020) Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome PharmaNutrition. 2020 Jun;12:100190.  Published online 2020 Apr 21. https://www.sciencedirect.com/science/article/abs/pii/S2213434420300153
  6. Caly L et al, 2020, Antiviral Research, 178, june 2020, 104787.
    https://www.sciencedirect.com/science/article/pii/S0166354220302011?via%3Dihub
  7. https://clinicaltrials.gov/ct2/show/NCT04747574

Zinc is important for the immune system

– also for Covid-19 disease

May 18 2020

In continuation of the previous two newsletters on Vitamin D and Selenium, a little important information about Zinc and its importance to the immune system is now presented here.

In these corona times, it is especially necessary that we each optimize our immune system so that we are well prepared for a possible new wave in about half a year from now, when people’s deposits of vitamin D again are declining.

In the Western part of the world, about 25% of the population has some level of zinc deficiency, especially the elderly, people with high alcohol consumption, people with chronic infections, those who get certain types of medicine, and elite athletes, who use up their magnesium and zinc.

Zinc is part of more than 200 different enzyme systems and is a prerequisite for normal growth and cell formation and a well-functioning immune system.

There is solid evidence that zinc deficiency leads to increased susceptibility to infection. Since zinc supplementation has also been found to reduce the duration of a cold, various zinc lozenges have been tried, and a Cochrane study of 18 studies found that 75 mg of zinc a day could reduce the duration of cold symptoms in healthy people, provided the zinc tablets were given within the first 24 hours after symptom onset.

The effect lies, among other things, in the skin and mucous membranes, where zinc is necessary for the cell replication that the body initiates when an infection is to be fought. This is especially true regarding the growth, maturation and differentiation of circulating lymphocytes, T cells and the killer cells, NK cells that we need to fight viruses.

In 2010, an in vitro study showed that zinc inhibits another coronavirus, namely SARS-CoV, which caused an epidemic in 2002. Zinc has a direct antiviral effect by inhibiting SARS-CoV RNA polymerase, which is a prerequisite for virus replication.

There is no specific study yet on the effect of zinc on the current CoV-Sars-2, but natural connections are looked for and, for example, the current Covid-19 disease is characterized by many people’s losing the sense of taste and smell, which is also seen in the case of zinc deficiency.
But it could be coincidence.

We have to take zinc all the time, as it is not stored specifically. It is not difficult to get enough zinc here in Denmark, just by eating real food and not industrial synthetic ‘plastic’ food. Zinc is found in meat, seafood, organ meat, fish, eggs, legumes, cereals, dairy products, green vegetables, fruits and berries. An intake of 20-30 mg per day is enough.

If you take zinc as a supplement, remember that it can reduce the copper content of the body, as zinc will upregulate the metallothionein synthesis, which can cause copper loss. This is probably not of great importance here in Denmark, where a large pig production has given us all a solid copper supplement.

In any case, we need zinc to optimize our immune system, so we are ready to fight an virus infection.

Now you have read about vitamin D, selenium and zinc in relation to the immune system.
The next newsletter to arm your immune system against Covid-19 will be about Vitamin C.

Take care of yourself and others,

Claus Hancke, MD,
Specialist in general medicine

Refs:

  • Read Scott A, Obeid S et al. The role of Zinc in antiviral immunity.(2019) Adv Nutr 2019;10:696–710
  • Skalny et al: Zinc and respiratory tract infections: Perspectives for Covid-19. Int J Molecular Med. April 13, 2020
  • Mossad S, Macknin M, Mendendorp S, et al. Zinc Gluconate Lozenges for Treating the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Study. Annals of Internal Medicine 15 July 1996
  • Velthuis AJW, van den Worm SHE, Sims AC, Baric RS, Snijder EJ, van Hemert MJ (2010). Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture. PLoS Pathog 6(11): e1001176.
  • Shankar AH, Prasad AS. Zinc and immune function: The biological basis of altered resistance to infection. Am J Clin Nutr. 1998 Aug;68 (2 Suppl): 447S-463S. doi: 10.1093/ajcn/68.2.447S.
  • Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD001364. DOI: 10.1002/14651858.CD001364.pub4
  • Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 2007;7(6):454–65.